First of all, this is frggin' epic. The shading is very well done, as well as the anatomy. Though, as with everything, it has its flaws.
I'mm start with the vision, kay? Vision is awesome. The picture is very clear and not just a tiny blob of pixel like Pokemon pixels, and honestly, I am hecka' surprised this is done with pixels. You are absolutely amazing! And I can tell you like to draw her a lot. XD
Originality. Hmm.. I always found your Pakicetus to be very unique, but that's besides the point. Hmm.. These poses look very neat, with a few flaws, and very canine-y. It's not everyday you see a snarling purple and blue wolf-fish-dolphin with a butt tattoo. XD
Technique.. Here's the big load of bajambaloo. I absolutely ADORE how you shaded it; not being too blunt, but not too skimpy. It really brings out the character, making her seem powerful when enraged, and quite possibly-- scary. And here's the part about the pose. The flaws, anyways. With the large sprite, her right (viewer's right) leg should at least be visible by the paw and part of the thigh. And the left (viewer's left), the leg part should also be visible, just about a few centimeters, and then the paw. And the front left (viewer's left) leg is a bit too bent with the elbow. Aaaaand the right (viewer's rightt) paw seems a bit too.. large and fluffy compared to her other paw. I see not problems with the anatomy of the smaller sprite except her head looks a bit too flat at the forehead.
The impact.. That's.. how it makes me feel, right? The emotions it invokes? Oh.. Hm.. Let's see. When looking at her, I feel a bit like she is going to pounce and rip someone's or something's intestines out, so maybe.. anger?